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Increased T1 signal

Fat

Blood

Calcification

IV contrast

Increased protein content

Melanin

mineralizing microangiopathy

Etiology:

usually from XRT and/or chemotherapy in children

chronic venous hypertension

Location of calcifications:

basal ganglia (Ca++ unusual <40)

subcortical white matter

mineralizing microangiopathy

Ca++ occurs in the walls of precapillary arterioles, capillaries, and venules as well as lenticulostriate vessels.

Perivascular neuronal calcification also occurs.

Hyper or hypointense on T1.

Hypointense on T2.