Go Back Brain/15. Brain and meninges, Infratentorial/Neoplasm, Neoplasm-like condition/15.3 - Hemangioblastoma Von Hippel Lindau/ Go to Index
Hemangioblastoma
Metastasis
Astrocytoma/Anaplastic Astrocytoma/GBM
Medulloblastoma
Subependymoma
Abscess.
Incidence: most common primary intra-axial neoplasm in the infra-tentorial space in adults
Site: cerebellum (83%), Spinal cord (10%), Medulla (2-3%)
Mean age of presentation: 39 yrs
Polycythemia 10-40%.
CT/MR
Structure
Cyst with solid mural nodule (55%)
Solid (40%)
Marked enhancement of solid portion
Serpentine flow voids of feeding vessels.
Small highly vascular nodule within an avascular mass
Intense, prolonged vascular stain
Occasionally with A-V shunting.
10-20% of HB in setting of vHL
45% vHL get HB
Lesions
Cysts (59-72%): Renal, Pancreatic, hepatic, epipidymal
Renal Cell Carcinoma (27-51%)
Pheochromocytoma (10%)
Pancreatic islet cell tumors.